| SISTER (PI: Aziz) | ID IMR (PI: Aziz) | STEP-Domain A (Low NIHSS) (PI: Demel) | STEP-Domain A (MVO/DMVO) (PI: Demel) | |
|---|---|---|---|---|
| LVO Required | LVO not required Anterior circ perfusion mismatch | ICA/M1/M2 (any) | ICA or M1 MCA Presents to enrolling hospital w/in 24h of LKW | Non-dom/Co-dom M2/M3 Presents to enrolling hospital w/in 24h of LKW |
| Pre-stroke mRS | 0-2 | — | 0-2 | 0-2 |
| NIHSS | ≥4 | — | 0-5 | ≥8 |
| ASPECTS | ≥6 (≥7 if MRI) | — | >6 (>7 if MRI) | >6 (>7 if MRI) |
| MRI Capability | — | Must be able to undergo MRI | — | — |
| IV lytcis/Anticoagulants | No thrombolytics (IV/IA) | — | — | — |
| Thrombectomy Required | No | Yes | — | — |
| Thrombectomy Device | — | — | — | — |
| Final mTICI | — | 2c-3 | — | — |
