Intracranial pressure monitoring with and without brain tissue oxygen pressure monitoring for severe traumatic brain injury in France (OXY-TC) 

Intracranial pressure monitoring with and without brain tissue oxygen pressure monitoring for severe traumatic brain injury in France (OXY-TC) 

Optimization of brain oxygenation might improve neurological outcome after traumatic brain injury. The OXY-TC trial explored the superiority of a strategy combining intracranial pressure and brain tissue oxygen pressure (PbtO2) monitoring over a strategy of intracranial pressure monitoring only to reduce the proportion of patients with poor neurological outcome at 6 months. 

Read More

High arterial oxygen levels and supplemental oxygen administration in TBI: insights from CENTER‑TBI and OzENTER‑TBI

High arterial oxygen levels and supplemental oxygen administration in TBI: insights from CENTER‑TBI and OzENTER‑TBI

The effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in TBI is debated, and data from large cohorts of TBI patients are limited. We investigated whether exposure to high blood oxygen levels and high oxygen supplementation is independently associated with outcomes in TBI patients admitted to the ICU and undergoing mechanical ventilation.

Read More