Current Stroke Trials
RESEARCH COMMUNICATIONS:
CRC’s will call the 584-UCUC number and page will come across Clinical Communications as: “Research” at [location] – [CRC’s name] requesting. [CB number]
Cheat Sheet for ACUTE Studies
For any acute trial questions, contact Yasmin (412-913-8424)
| SISTER (PI: Aziz) | STEP-Domain A (Low NIHSS) (PI: Demel) | ID IMR (PI: Aziz) | ||||
|---|---|---|---|---|---|---|
| LVO Required | LVO not required Anterior circ perfusion mismatch | ICA or M1 MCA Presents to enrolling hospital w/in 24h of LKW | ICA/M1/M2 (any) | |||
| Pre-stroke mRS | 0-2 | 0-2 | — | |||
| NIHSS | ≥4 | 0-5 | — | |||
| ASPECTS | ≥6 (≥7 if MRI) | >6 (>7 if MRI) | — | |||
| MRI Capability | — | — | Must be able to undergo MRI | |||
| ICT/AC | No thrombolytics (IV/IA) | — | — | |||
| MT Required | No | — | Yes | |||
| MT Device | — | — | — | |||
| Final mTICI | — | — | 2c-3 | |||
| SISTER (PI: Aziz) | |
|---|---|
| LVO Required | LVO not required Anterior circ perfusion mismatch |
| Pre-stroke mRS | 0-2 |
| NIHSS | ≥4 |
| ASPECTS | ≥6 (≥7 if MRI) |
| MRI Capability | — |
| ICT/AC | No thrombolytics (IV/IA) |
| MT Required | No |
| MT Device | — |
| Final mTICI | — |
| ID IMR (PI: Aziz) | |
|---|---|
| LVO Required | ICA/M1/M2 (any) |
| Pre-stroke mRS | — |
| NIHSS | — |
| ASPECTS | — |
| MRI Capability | Must be able to undergo MRI |
| ICT/AC | — |
| MT Required | Yes |
| MT Device | — |
| Final mTICI | 2c-3 |
| STEP-Domain A (Low NIHSS) (PI: Demel) | |
|---|---|
| LVO Required | ICA or M1 MCA Presentation to enrolling hospital w/in 24h of LKW |
| Pre-stroke mRS | 0-2 |
| NIHSS | 0-5 |
| ASPECTS | >6 (>7 if MRI) |
| MRI Capability | — |
| ICT/AC | — |
| MT Required | — |
| MT Device | — |
| Final mTICI | — |
Trial Finder: https://stroke-trial-finder.ajai.dev/f/cincinnati/
