AIS

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TNK Eligibility
  • Patients of any age with suspected ischemic stroke within 4.5 hours of last known well.
  • Selected patients beyond 4.5 hours from last known well, with unwitnessed time of onset.
  • See more details regarding eligibility criteria below (GWTG Goal Times).
ID-IMR
ID-IMR— (PI: Aziz)
LVO Required
ICA/M1/M2 (any)
LKW
24 hrs
Pre-stroke mRS
—
NIHSS
—
ASPECTS
—
MRI Capability
Must be able to undergo MRI
ICT/AC
—
MT Required
Yes
MT Device
—
Final mTICI
2c-3

ORDER to USE: XXXXXXX
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ACTIVE SITES: XXXXXXX
Clinicaltrials.gov
SISTER
SISTER — (Stite PI: Aziz)
LVO Required
  1. LVO not required
  2. Anterior circ perfusion mismatch
LKW
4.5 – 24 hrs
Pre-stroke mRS
0 - 2
NIHSS
≥4
ASPECTS
>6 (>7 if MRI)
MRI Capability
—
ICT/AC
No Thrombolytics (IV/IA)
MT Required
No
MT Device
—
Final mTICI
—

ORDER to USE: XXXXXXX
AFTER HOURS CALL: XXXXXXX
ACTIVE SITES: XXXXXXX
Clinicaltrials.gov
STEP DOMAIN A (Low NIHSS)
STEP-Domain A (Low NIHSS) — (PI: Demel)
LVO Required
ICA or M1 MCA
LKW
24 hrs
Pre-stroke mRS
0-2
NIHSS
0-5
ASPECTS
>6 (>7 if MRI)
MRI Capability
—
ICT/AC
—
MT Required
—
MT Device
—
Final mTICI
—

ORDER to USE: XXXXXXX
AFTER HOURS CALL: XXXXXXX
ACTIVE SITES: XXXXXXX
Clinicaltrials.gov
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Taming NICU